Prelone Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing

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Special instructions need to be followed while taking this medicine along with warfarin and other coumarins, which are used to prevent blood clot formation. The combined use of corticosteroids and warfarin usually prevents the response of warfarin. Coagulation parameters should be monitored to maintain the desired anticoagulant effect. Children, young adults and women who are undergoing or have undergone menopause are at a higher risk. Corticosteroids decrease bone formation because of decreased absorption and increased removal of calcium in the body. This increases the risk of osteoporosis in children, young adults and women who are undergoing or have undergone menopause.

When stopping this medicine, some patients may experience withdrawal symptoms like an insufficient production of steroid hormones , and low blood pressure. You may need to taper the dose of this medicine when stopping. Prednisolone is administered orally, while prednisolone sodium phosphate may be administered orally or by IM, IV, intra-articular, intrasynovial, intralesional, or soft tissue injection or by IV infusion. The prednisolone acetate preparation may be administered by IM, intra-articular, or soft tissue injection.

Reserve systemic corticosteroid therapy in active tuberculosis for patients with fulminating or disseminated disease and only in conjunction with appropriate antituberculosis therapy. Reactivation of tuberculosis may occur in patients with latent tuberculosis or tuberculin reactivity; close observation for disease reactivation is needed if corticosteroids are indicated in such patients. Furthermore, chemoprophylaxis is advised if prolonged corticosteroid therapy is needed. Instruct patients to get immediate medical advice if exposure occurs.

In some cases, health care professionals may use the trade names Prelone, Delta-Cortef, Orapred, and Pediapredwhen referring to the generic drug name Prednisolone. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Store this medication according to the directions on the product package away from light and moisture.

If exposed to chickenpox, prophylaxis with varicella-zoster immune globulin may be indicated. If exposed to measles, prophylaxis with pooled intramuscular immunoglobulin may be indicated. Avoid the use of corticosteroids in active ocular herpes infection due to the risk of corneal perforation. Prednisolone has been used in infants, children, and adolescents; however, consider pediatric-specific issues before initiating treatment.

Some Medicare plans may help cover the cost of mail-order medications. Keep in mind that you may be able to get a 90-day supply of prednisolone. If approved by your insurance company, getting a 90-day supply of the drug could reduce your number of trips to the pharmacy and help lower the cost. Below is a table of medications that can interact with prednisolone. This table does not contain all drugs that may interact with prednisolone. Before taking prednisolone, talk with your doctor and pharmacist.

This is a type of rare blood cancer that typically begins as a skin rash. Eventually, the rash may turn to crusty or scaly skin patches. This skin condition is thought to occur when the immune system attacks the skin. Endocrine conditions occur when the endocrine system does not function correctly. † To learn more about long-term side effects of prednisolone, see the “Prednisolone side effects” section above. Your doctor can advise how long to take prednisolone based on your specific condition.